SELECTED PUBLICATIONS
 

  1. Pinton L, Khedr M, Lionello V, Sarcar S, Maffioletti SM, Dastidar S, Negroni E, Choi SW, Khokhar N, Bigot A, Counsell JR, Zammit PS, Tedesco FS. 3D Human Induced Pluripotent Stem Cell-derived Bioengineered Skeletal Muscles for Tissue, Disease and Therapy Modelling. Protocols Exchange 2022, doi.org/10.21203/rs.3.pex-2034/v1

  2. Choi SW, Ferrari G, Moyle LA, Mackinlay K, Naouar N, Jalal S, Benedetti S, Wells C, Muntoni F, Tedesco FS. Assessing and enhancing migration of human myogenic progenitors using directed iPS cell differentiation and advanced tissue modelling. EMBO Molecular Medicine, 2022 Oct 10;14(10):e14526. doi: 10.15252/emmm.202114526.

  3. Jalal S, Dastidar S, Tedesco FS. Advanced models of human skeletal muscle differentiation, development and disease: iPS cell-derived myogenic progenitors, organoids and beyond. Current Opinion in Cell Biology, 2021 Aug 9;73:92-104. doi: 10.1016/j.ceb.2021.06.004 (Cover)

  4. Choi SW, Ferrari G, Tedesco FS. Cellular dynamics of myogenic cell migration: molecular mechanisms and implications for skeletal muscle cell therapies. EMBO Molecular Medicine, 2020 Nov 19:e12357. doi: 10.15252/emmm.202012357

  5. Ferrari G, Muntoni F, Tedesco FS. Generation of two genomic-integration-free DMD iPSC lines with mutations affecting all dystrophin isoforms and potentially amenable to exon-skipping. Stem Cell Research, 2020 Feb 1;43:101688. doi: 10.1016/j.scr.2019.101688

  6. Gerli MFM, Moyle LA, Benedetti S, Ferrari G, Ucuncu E, Ragazzi M, Constantinou C, Louca I, Sakai H, Ala P, De Coppi P, Tajbakhsh P, Cossu G, Tedesco FS. Combined Notch and PDGF Signalling Enhances Migration and Expression of Stem Cell Markers while Inducing Perivascular Cell Features in Muscle Satellite Cells. Stem Cell Reports, 2019 Mar 5;12(3):461-473. doi.org/10.1016/j.stemcr.2019.01.007  

  7. Steele-Stallard H, Pinton L, Sarcar, S, Ozdemir T, Maffioletti SM, Zammit PS, Tedesco FS. Modelling Skeletal Muscle Laminopathies Using Human Induced Pluripotent Stem Cells Carrying Pathogenic LMNAmutations. Frontiers in Physiology, 2018 Oct 15;9:1332. doi: 10.3389/fphys.2018.01332

  8. Maffioletti SM, Sarcar S, Henderson ABH, Mannhardt I, Pinton L, Moyle LA, Steele-Stallard H, Cappellari O, Wells KE, Ferrari G, Mitchell JS, Tyzack GE, Kotiadis VN, Khedr M, Ragazzi M, Wang W, Duchen MR, Patani R, Zammit PS, Wells D, Eschenhagen T, Tedesco FS. Three-dimensional Human iPSC-derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering. Cell Reports 2018 Apr 17;23(3):899-908. doi: 10.1016/j.celrep.2018.03.091. (F1000 recommended)

  9. Benedetti S, Uno N, Hoshiya H, Ragazzi M, Ferrari G, Kazuki Y, Moyle LA, Tonlorenzi R, Lombardo A, Chaouch A, Mouly V, Moore M, Popplewell L, Kazuki K, Katoh M, Naldini L, Dickson G, Messina G, Oshimura M, Cossu G, Tedesco FS. Reversible Immortalisation Enables Genetic Correction of Human Muscle Progenitors and Engineering of Next-Generation Human Artificial Chromosomes for Duchenne Muscular Dystrophy. EMBO Molecular Medicine, 2017 Dec 14. doi: 10.15252/emmm.201607284.

  10. Maffioletti SM, Gerli MFM, Ragazzi M, Dastidar S, Benedetti S, Loperfido M, VandenDriessche T, Chuah M, Tedesco FS. Efficient Derivation and Inducible Differentiation of Expandable Skeletal Myogenic Cells from Human ES and Patient-Specific iPS Cells. Nature Protocols, 2015 Jun 4; 10, 941–958 (cover article)

  11. Tedesco FS, Gerli M, Perani L, Benedetti S, Ungaro F, Cassano M, Antonini S, Tagliafico E, Artusi V, Tonlorenzi R, Ragazzi M, Calderazzi G, Hoshiya H, Cappellari O, Mora M, Sampaolesi M, Torrente Y, Broccoli V and Cossu G Transplantation of Genetically Corrected Human iPSC-Derived Progenitors in Mice with Limb-Girdle Muscular Dystrophy. Science Translational Medicine, 2012 Jun 27;4(140):140ra89

  12. Tedesco FS, Hoshiya H, D’Antona G, Gerli M, Messina G, Antonini S, Tonlorenzi R, Benedetti S, Berghella L, Torrente Y, Kazuki Y, Bottinelli R, Oshimura M and Cossu G.  Stem cell-mediated transfer of a human artificial chromosome ameliorates muscular dystrophy. Science Translational Medicine 2011 Aug 17;3(96):96ra78 (Cover Article)

  13. Tedesco FS, Dellavalle A, Diaz-Manera J, Messina G, Cossu G. Repairing skeletal muscle: regenerative potential of skeletal muscle stem cells. Journal of Clinical Investigation 2010 Jan;120(1):11-9